Diltiazem EP Impurity F HCl CAS 75472-91-2(free base)
| CAS No. | 75472-91-2(free base) |
| Molecular Formula | C20H24N2O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Diltiazem EP Impurity F HCl (CAS 75472-91-2(free base)), a pharmacopoeial impurity reference standard (molecular formula C20H24N2O3SHCl, MW 408.94 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H24N2O3SHCl, Diltiazem EP Impurity F HCl contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Diltiazem EP Impurity F HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O3S HCl |
| Molecular Weight | 408.94 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem EP Impurity A HCl (CAS 103532-27-0)
- Diltiazem EP Impurity A HCl (CAS 111188-71-7(free base))
- Diltiazem D4 (CAS 112259-41-3)
- Diltiazem USP Related Compound H HCl (CAS 115992-91-1(Free Base))
- Diltiazem EP Impurity H HCl (CAS 115992-91-1(free base))
- Diltiazem Impurity 9 (CAS 116050-35-2)
- Diltiazem Impurity 23 (CAS 119009-50-6)
- Diltiazem-d3 Hydrochloride (CAS 1217623-80-7)
Recommended Standards
- Piracetam impurity 34 (CAS CATO-C4X-123534)
- Ceftaroline Impurity 3 (CAS 1286218-68-5)
- Ethosuximide impurity 5 (CAS CATO-C4X-26255)
- Linezolid Impurity 64 (CAS CATO-C4X-107364)
- (E)-2-(Thiophen-2-yl)ethene-1-sulfonyl fluoride (CAS 2093304-41-5)
- 2,3-Dihydropyrido[2,3-d]pyrimidin-4(1H)-one (CAS 204933-50-6)
- N-(9H-Fluoren-2-yl)benzamide (CAS 3671-78-1)
- Ethyl dimethylsulfamate (CAS 75013-50-2)
- Methyl 6-fluoro-1,2,3,4-tetrahydroisoquinoline-1-carboxylate hydrochloride (CAS 2007908-42-9)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com